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Metastatic Thymoma

Metastatic Thymoma▶ Watch on YouTube — age-restricted, cannot embed here

Imaging findings

Initial presentation in 2005 showed an anterior mediastinal mass that was lobulated, contained some calcium, and caused mass effect on the lung, characteristic of a thymic neoplasm. By 2007, post-resection, there was pericardial fluid, thickening of the pericardium and pleura, subtle nodularity along the diaphragmatic pleura, and a pleural nodule, consistent with pleural metastasis. Progressive growth of tumor nodules along the pleural surface and in the lower mediastinum (perithymic and perisalvageal nodes) was observed in 2011 and 2015, with associated effusion.

Key takeaways

Thymomas, even those considered low-grade histologically, can recur locally and metastasize. Metastases can grow slowly over many years, as demonstrated by this 10-year progression, often remaining confined primarily to the affected hemithorax and adjacent fat.

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