CTICasesInvasive Mucinous Adenocarcinoma Mimicking Interstitial Lung Disease
Imaging findings
CT reveals highly asymmetric pulmonary changes with areas of ground-glass opacity, consolidation, crazy-paving pattern, and widespread cystic lung destruction, initially misdiagnosed as fibrosing interstitial lung disease. Centrilobular nodules in the contralateral lung suggest airway-centered or aerogenous spread.
Key takeaways
Lung biopsy confirmed invasive mucinous adenocarcinoma of the lung. This case serves as a vital reminder that diffuse or asymmetric bronchioloalveolar-type carcinomas (adenocarcinoma with lepidic or mucinous growth) can closely mimic progressive interstitial lung disease, particularly when presenting with ground-glass opacities, crazy-paving, and cystic changes. Rapid clinical progression or failure to respond to immunosuppressive therapy should prompt early histological sampling to rule out malignancy.
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