CTICasesPOEMS Syndrome with Castleman's Disease
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Imaging findings
Imaging showed enhancing lymph nodes in the right axilla and right subpectoral region, in addition to multiple sclerotic bone lesions.
Key takeaways
POEMS syndrome (Polyneuropathy, Organomegaly, Endocrinopathy, Monoclonal gammopathy, Skin changes) is a rare paraneoplastic syndrome that can be associated with Castleman's disease (angiofollicular lymphoid hyperplasia). Patients present with a variety of symptoms and imaging findings, including polyneuropathy, organomegaly, endocrinopathy, monoclonal spike, sclerotic bone lesions, and lymphadenopathy, fitting specific major and minor diagnostic criteria for the syndrome.
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