CTICasesPost-Transplantation Lymphoproliferative Disorder (PTLD)
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Imaging findings
The patient, with a history of liver and kidney transplantation, showed extensive intrathoracic and extrathoracic lymph node enlargement, particularly paratracheal. A nodule in the left lower lung was also identified, which was PET-avid, similar to other soft tissue lesions and lymph nodes. Biopsy confirmed diffuse large B-cell lymphoma.
Key takeaways
Post-transplantation lymphoproliferative disorder (PTLD) is a serious complication in transplant recipients due to immunosuppression. It can manifest as diffuse large B-cell lymphoma, presenting with widespread lymphadenopathy and PET-avid soft tissue lesions or lung nodules, necessitating biopsy for definitive diagnosis.
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