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Hemodynamically Insignificant LAD Stenosis on CTFFR

Imaging findings

Coronary CT angiography shows anatomically severe stenosis at the LAD/diagonal/septal branch trifurcation. CT-derived fractional flow reserve (CTFFR) was normal (FFR > 0.80), corresponding with a normal stress perfusion study.

Key takeaways

Anatomically severe stenoses on coronary CTA can be hemodynamically insignificant due to patient-specific flow dynamics. CT-derived FFR provides non-invasive functional assessment, helping avoid unnecessary diagnostic catheterization.

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