CTICasesGranulomatosis with Polyangiitis with Superimposed COVID-19
Imaging findings
CT in a patient with a history of sinus disease and cavitating lung nodules from granulomatosis with polyangiitis (GPA) shows new, progressive diffuse consolidations and ground-glass opacities, representing acute COVID-19 infection rather than alveolar hemorrhage.
Key takeaways
Patients with underlying autoimmune vasculitides such as GPA are at high risk for severe pulmonary manifestations and robust cytokine responses when infected with COVID-19. Differentiating active vasculitis flare or alveolar hemorrhage from viral pneumonia requires clinical correlation and PCR testing.
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