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Silicosis with Galaxy Sign and Pseudoplaques

Imaging findings

CT in a patient with biopsy-proven silicosis shows large, central progressive massive fibrosis (PMF) masses displaying the 'galaxy sign' of clustered nodules, along with calcified paraesophageal lymph nodes and calcified subpleural deposits (pseudoplaques).

Key takeaways

The 'galaxy sign' of a large mass surrounded by satellite nodules is classic for sarcoidosis but can also be seen in silicosis. Finding calcifications in subpleural pseudoplaques and paraesophageal lymph nodes strongly points to silica exposure.

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