CTICasesMucormycosis with Dissemination to Brain in a Renal Transplant Patient
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Imaging findings
Chest radiograph reveals extensive pathology in the right lower and middle lobes with a subtle area of cavitation. CT shows a reverse halo sign and a reticular 'bird's nest sign' in the right middle lobe, with central cavitation, and another cavitary focus, plus pleural fluid. Subsequent imaging showed a small brain lesion consistent with dissemination and worsening cavitation in the lungs, eventually requiring drainage.
Key takeaways
Mucormycosis is a rapidly progressive and severe opportunistic fungal infection, especially in immunosuppressed transplant patients. Imaging findings like the reverse halo sign, bird's nest sign, and cavitation are highly suggestive. Dissemination, including to the brain, can occur. Early diagnosis and antifungal treatment are critical for patient outcomes.
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