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Adenocarcinoma with Lymphangitic Spread Mimicking Radiation Fibrosis

Adenocarcinoma with Lymphangitic Spread Mimicking Radiation Fibrosis▶ Watch on YouTube — age-restricted, cannot embed here

Imaging findings

CT shows focal ground-glass opacity within a region, a central mass, septal thickening, and bronchiectasis. The appearance has been long-standing.

Key takeaways

This case serves as a mimic of post-radiation pneumonitis and fibrosis. The persistence of the appearance for much longer than the typical time course for radiation pneumonitis suggests an alternative diagnosis. The findings represent adenocarcinoma with a desmoplastic response causing bronchodilatation and likely lymphangitic spread, in a patient with no history of radiotherapy.

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