CTICasesAdult-Onset Cystic Fibrosis (with Pancreatic Fatty Atrophy)
▶ Watch on YouTube — age-restricted, cannot embed here
Imaging findings
In the first patient, CT reveals subtle tracheal wall thickening, diffuse bronchial thickening, and clustered centrilobular nodules in the middle lobe. Abdominal imaging demonstrates near-complete fatty atrophy of the pancreas. A comparative second patient, a 72-year-old, showed bronchial wall thickening and tree-in-bud nodularity.
Key takeaways
Adult-onset cystic fibrosis can present with subtle lung findings like mild bronchial thickening and centrilobular nodules, along with pancreatic fatty atrophy, even at older ages. It's an important differential to consider in patients with chronic cough and pancreatic atrophy, despite mild lung disease that may not be severely progressed.
AI-assisted summary — may contain errors. Verify against the source video. Learn more
More from this webinar
- Pericardial Fat Pad Torsion / Spontaneous Necrosis of Mediastinal FatInflammatory
- Embolized Amplatzer Vascular Plugs Causing ClaudicationIatrogenic
- Adenocarcinoma with Lymphangitic Spread Mimicking Radiation FibrosisNeoplastic
- Diffuse Idiopathic Pulmonary Neuroendocrine Cell Hyperplasia (DIPNECH)Neoplastic
- Paraspinal GanglioneuromaNeoplastic
- Extramedullary Hematopoiesis in ThalassemiaMetabolic
- Multicentric Castleman's Disease (HHV-8 Associated, Plasma Cell Type)Neoplastic
- Unicentric Castleman's Disease (Hyaline Vascular Type)Neoplastic
See all cases from January 25, 2016 →
Related Congenital cases
- Pentalogy of Cantrell
- Hybrid Congenital Lesion: CPAM, Sequestration, and Bronchial Atresia
- Intramyocardial Fatty Foci (Tuberous Sclerosis)
- Proximal Interruption of the Right Pulmonary Artery with Coronary Collaterals
- Pseudo-Accessory Fissure with Bronchial Herniation/Hyperinflation
- Proteus Syndrome with Severe Emphysema