CTICasesChronic Vaping-Induced Lung Fibrosis
Imaging findings
Serial imaging from 2017 to 2021 shows progressive, severe loss of lung volume and diffuse, bilateral, upper-lung-predominant lung disease. High-resolution CT demonstrates a widespread interstitial pattern resembling non-specific interstitial pneumonia (NSIP) with extensive reticulation, diffuse ground-glass opacities, traction bronchiectasis, and peripheral sparing. Over time, the disease progresses to end-stage fibrosis accompanied by signs of severe pulmonary hypertension, including a massively dilated pulmonary artery, mediastinal lymphadenopathy, and spontaneous pneumomediastinum.
Key takeaways
Chronic heavy vaping can result in severe, progressive, and potentially fatal inhalational lung injury leading to widespread pulmonary fibrosis. The upper-lung-predominant distribution of reticulation and NSIP-like fibrosis strongly supports an inhalational etiology. In severe cases, this injury can lead to end-stage respiratory failure and pulmonary hypertension, requiring bilateral lung transplantation.
AI-assisted summary — may contain errors. Verify against the source video. Learn more
More from this webinar
- Solitary Fibrous Tumor of the PleuraNeoplastic
- ROR1 CAR T-Cell Therapy-Induced Cytokine Release SyndromeInflammatory
- Ruptured Dobhoff Feeding TubeIatrogenic
- Foreign Body Granuloma from BioSentry Biopsy Tract SealantInflammatory
- Circumflex Aortic ArchCongenital
- Double Aortic Arch with Atretic Left Segment and Secundum ASDCongenital
- Pulmonary HistoplasmosisInfection
- Ruptured Post-Operative Aortic Root PseudoaneurysmVascular
See all cases from April 30, 2021 →