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Pulmonary infarction mimicking lung malignancy on PET/CT

Imaging findings

CT shows a right upper lobe consolidation. PET/CT shows high metabolic activity (SUV 10) in the consolidation and hilum. Retrospective review of a prior non-contrast CT shows a hyperdense clot in the right upper lobe pulmonary artery, confirming a pulmonary infarction.

Key takeaways

Acute pulmonary infarction can demonstrate intense FDG avidity on PET/CT, mimicking a primary lung malignancy or active infection. Reviewing the vascular patency (or checking for hyperdense clots on prior non-contrast scans) is crucial to avoid diagnostic errors.

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