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Pulmonary veno-occlusive disease (PVOD) with pulmonary venous thrombosis

Imaging findings

CT angiogram shows patent pulmonary arteries but macroscopic filling defects and thrombosis in the right superior and left lower pulmonary veins, accompanied by interlobular septal thickening and pulmonary edema.

Key takeaways

PVOD is a rare form of pulmonary hypertension characterized by obstruction of the pulmonary venules. Rarely, it can manifest with macroscopic thrombosis of the larger pulmonary veins. The V/Q scan can mimic CTEPH by showing mismatched perfusion defects.

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