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Neovascularity in Pulmonary Hypertension

Imaging findings

CT in a patient with severe idiopathic pulmonary arterial hypertension shows dilated central pulmonary arteries and diffuse, smudgy centrilobular ground-glass opacities, with tortuous, corkscrewing small vessels extending to the pleural surface.

Key takeaways

Severe pulmonary hypertension can lead to capillary remodeling and neovascularity (dilated, congested capillaries and adventitial vessels). This manifests as centrilobular ground-glass opacities and corkscrewing small vessels distinct from plexiform lesions.

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