CTICasesMetastatic Colloid Carcinoma of the Pancreas
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Imaging findings
Chest CT demonstrates extensive mediastinal, retroperitoneal, and peripancreatic lymphadenopathy characterized by a bizarre, amorphous pattern of calcification. The pancreatic tail demonstrates surgical changes and residual tumor with similar dense calcifications.
Key takeaways
Metastasis from mucin-producing gastrointestinal primaries, such as colloid carcinoma of the pancreas (often arising from intraductal papillary mucinous neoplasms, or IPMN), can present with extensive, dense, or amorphous nodal calcification. This highly atypical calcification pattern should not be mistaken for benign, old granulomatous disease, especially in patients with a history of GI malignancy.
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