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Endobronchial Metastasis from Melanoma

Endobronchial Metastasis from Melanoma▶ Watch on YouTube — age-restricted, cannot embed here

Imaging findings

Initial chest CT shows a tiny endobronchial nodule in the right mainstem bronchus, initially interpreted as retained secretions. Follow-up CT obtained three months later reveals rapid interval growth into a large endobronchial mass invading the posterior wall of the right mainstem bronchus.

Key takeaways

Melanoma, along with renal cell carcinoma, is a tumor that has a high propensity for endobronchial metastasis. What may appear on imaging as a small, benign-looking endobronchial nodule or retained secretions should be followed closely or biopsied in patients with a history of melanoma, as these lesions can rapidly enlarge and cause acute airway obstruction.

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