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Strongyloides Hyperinfection

Imaging findings

CT chest shows diffuse tree-in-bud and centrilobular nodules, ground-glass opacities, and areas of consolidation. The patient has a history of AML post-bone marrow transplant and is severely neutropenic. Universal PCR of BAL and stool O&P confirmed Strongyloides.

Key takeaways

Strongyloides hyperinfection is a life-threatening complication in immunocompromised hosts. Larvae migrate from the GI tract to the lungs, causing acute lung injury, ARDS, and secondary bacterial infections. Radiographically, it presents with diffuse ground-glass, consolidations, and centrilobular/tree-in-bud nodules.

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