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Cystic Pulmonary Metastases from Lung Adenocarcinoma

Imaging findings

CT in a patient with treated metastatic adenocarcinoma of the lung shows multiple thin-walled, imperceptible cystic spaces in areas where solid pulmonary nodules were previously documented, representing a response to targeted egfr or checkpoint inhibitor therapy.

Key takeaways

Pulmonary metastases from adenocarcinoma or sarcoma can undergo cavitation and resolve into thin-walled, air-filled cysts following successful chemotherapy or targeted molecular therapy, which should not be confused with progressive cavitating disease.

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