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Giant Type B Thymoma

Imaging findings

CT shows a very large, aggressive-appearing anterior mediastinal soft tissue mass interspersed with fat, extending into the left chest. Surprisingly, there was no pleural seeding or metastases despite the massive size. The mass was treated with radiation and chemotherapy followed by extrapleural pneumonectomy, confirming a Type B thymoma.

Key takeaways

Thymomas can grow to a massive size and mimic aggressive sarcomas or malignancies. The lack of pleural seeding or metastatic disease on staging, even for a very large mass, is a helpful clue favoring a thymoma over a primary pleural sarcoma.

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