CTICasesPulmonary Cryptococcosis
Imaging findings
Chest CT in a renal transplant recipient shows large, well-defined, rounded pulmonary nodules in the right lower lobe. The nodules track along the bronchovascular bundle and show minimal central necrosis or cavitation, with associated enlargement of adjacent subcarinal and hilar lymph nodes.
Key takeaways
Pulmonary cryptococcosis is a common fungal opportunistic infection in immunocompromised hosts, such as solid organ transplant recipients. Unlike histoplasmosis, which often presents with smaller, calcified nodules, cryptococcosis typically manifests as large, well-circumscribed, non-calcified nodules or masses that can mimic malignancy. It can also present with variable features such as consolidation and lymphadenopathy.
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