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Cystic Sarcoidosis in HIV

Imaging findings

Chest radiograph and CT of a patient with well-controlled HIV show multiple small perilobular nodules along the bronchovascular bundles and fissures, along with atypical, confluent cystic spaces in the middle lobe and lingula.

Key takeaways

Sarcoidosis can rarely present with atypical cystic or bubbly lung changes, which typically track along the bronchovascular bundles. This must be distinguished from lymphocytic interstitial pneumonitis (LIP) or other HIV-associated lung diseases.

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