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Mediastinal Parathyroid Adenoma

Imaging findings

CT chest shows a small, well-circumscribed, hypervascular soft tissue nodule in the superior mediastinum near the right sternoclavicular joint. Sestamibi scintigraphy confirmed a hyperfunctioning ectopic parathyroid adenoma.

Key takeaways

Ectopic parathyroid adenomas can migrate during embryological development and localize in the superior mediastinum or thymus. They can be extremely subtle on CT, requiring dedicated multiphase CT (4D-CT) or sestamibi scintigraphy for localization prior to surgical resection.

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