CTICasesChronic Hypersensitivity Pneumonitis
Imaging findings
CT chest shows upper-lobe predominant reticular opacities, traction bronchiectasis, and bronchovascular bundle thickening, with relative sparing of the lung bases. Histology shows airway-centric interstitial fibrosis and rare non-necrotizing granulomas.
Key takeaways
Chronic hypersensitivity pneumonitis (HP) is an immunologically mediated ILD caused by inhaled antigens. Key CT findings include upper-to-mid-lung predominant reticular opacities and airway-centric fibrosis. The presence of peribronchial non-necrotizing granulomas on biopsy helps exclude UIP.
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