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CTEPH with Intracerebral Hemorrhage on Anticoagulation

Imaging findings

CT brain shows a large acute intraparenchymal cerebral hematoma. Chest CT shows findings of chronic thromboembolic pulmonary hypertension (CTEPH), including web-like pulmonary artery filling defects and hypertrophied bronchial arteries. The patient has Factor V Leiden.

Key takeaways

Patients with hypercoagulable states (like Factor V Leiden) and chronic thromboembolic disease require life-long anticoagulation, placing them at high risk for major hemorrhagic complications such as intraparenchymal brain hemorrhage. CTEPH CT markers include arterial webs, stenosis, and collateral bronchial artery hypertrophy.

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