CTICasesPulmonary Mucormycosis
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Imaging findings
Chest radiograph shows an apical opacity in the remaining left lung. CT reveals a large cavitary lesion with internal necrosis, along with smaller associated opacities likely representing bronchiolar involvement. Biopsy demonstrated benign lung parenchyma with lymphoplasmacytic infiltrate and organizing pneumonia, showing non-septate hyphal elements on fungal stain. No significant narrowing of the left main bronchus was noted.
Key takeaways
Mucormycosis, an opportunistic fungal infection, can present as a cavitary lung lesion with internal necrosis. While direct culture may be negative, the presence of non-septate hyphal elements on histology is characteristic. Patients with diabetes or other immunosuppression are predisposed to such infections. Differential diagnosis includes other apical opportunistic infections like Nocardia or Cryptococcus.
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