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Diffuse Pulmonary Adenocarcinoma with Cystic Changes

Diffuse Pulmonary Adenocarcinoma with Cystic Changes▶ Watch on YouTube — age-restricted, cannot embed here

Imaging findings

The patient presents with very extensive diffuse lung disease. Contralateral lymph node enlargement is noted. A cystic area is also present, which does not appear as typical empyema, and is speculated to be related to the adenocarcinoma. Percutaneous biopsy confirmed diffuse adenocarcinoma.

Key takeaways

Diffuse pulmonary adenocarcinoma can present with widespread lung disease that may be initially confused with pneumonia, especially when refractory to treatment. The presence of unusual cystic spaces may also be a feature of diffuse adenocarcinoma, making diagnosis challenging.

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