CTICasesDouble-Hit Diffuse Large B-Cell Lymphoma Presenting as Chest Wall Mass
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Imaging findings
A 78-year-old male with a history of esophageal cancer (years prior) developed a large mass in his right lateral chest wall, aggressively involving the scapula, which grew rapidly over three months. Biopsy revealed a diffuse large B-cell lymphoma.
Key takeaways
Diffuse large B-cell lymphoma can present as an aggressive chest wall mass invading bone, mimicking a primary bone tumor or metastasis. The identification of 'double-hit' features (e.g., extra chromosome and translocation) indicates a particularly aggressive subtype of lymphoma with a worse prognosis.
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