CTICasesDiffuse Alveolar Hemorrhage in Mixed Connective Tissue Disease
Imaging findings
Initial CT shows a classic NSIP pattern of pulmonary fibrosis with subpleural ground-glass opacity and reticulation, along with pericardial and pleural thickening. Follow-up CT five days later shows rapid development of diffuse, bilateral consolidation, representing acute diffuse alveolar hemorrhage.
Key takeaways
Patients with lupus or mixed connective tissue disease can present with acute diffuse alveolar hemorrhage, which manifests as rapidly progressive bilateral consolidation and ground-glass opacity superimposed on chronic fibrosing interstitial lung disease.
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