CTICasesFollicular Bronchiolitis in Sjögren's Syndrome
Imaging findings
Chest CT shows diffuse, symmetric centrilobular ground-glass nodules throughout both lungs. There is also a mild pericardial effusion and fluid/debris retention in the patulous esophagus, representing manifestations of Sjögren's syndrome/mixed connective tissue disease overlap. Transbronchial biopsy confirmed follicular bronchiolitis.
Key takeaways
Follicular bronchiolitis is a hyperplasia of peribronchial lymphoid tissue. When encountered in a patient with connective tissue disease (like Sjögren's or rheumatoid arthritis), it typically presents as small, clean centrilobular ground-glass nodules, which must be distinguished from hypersensitivity pneumonitis or smoking-related bronchiolitis.
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