CTICasesLangerhans Cell Histiocytosis and Desquamative Interstitial Pneumonia
Imaging findings
Chest radiography demonstrates a highly concentrated, busy reticular abnormality in the upper and mid-lung zones. Computed tomography confirms a lacy interstitial pattern with a few thick-walled cystic spaces in the upper lungs, alongside extensive, basal-predominant ground glass opacities.
Key takeaways
In a cigarette smoker, the combination of upper-lung predominant cystic and nodular abnormalities with extensive basal ground glass opacities suggests a collision of smoking-related lung diseases, specifically Langerhans cell histiocytosis and desquamative interstitial pneumonia.
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