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Swyer-James-MacLeod Syndrome

Imaging findings

CT chest in an adult shows unilateral hyperlucency of the left lung with air trapping on expiration, severe pulmonary vascular rarefaction, and multiple cystic bronchiectatic spaces, secondary to severe childhood respiratory syncytial virus (RSV) infection.

Key takeaways

Swyer-James-MacLeod syndrome is a post-infectious sequela of childhood bronchiolitis obliterans (typically due to adenovirus or RSV). It causes unilateral pulmonary hypoplasia, bronchial obstruction, alveolar hyperinflation/air trapping, and secondary arterial hypoplasia.

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