Cardiac graft-versus-host disease (GVHD)
Imaging findings
Cardiac MRI in a bone marrow transplant recipient shows multiple areas of delayed myocardial enhancement (subendocardial, subepicardial, and transmural). Right ventricular endomyocardial biopsy confirmed lymphocytic myocarditis.
Key takeaways
Graft-versus-host disease (GVHD) rarely affects the myocardium. It can manifest as a fulminant lymphocytic myocarditis with extensive delayed enhancement and progressive heart failure, mimicking giant cell myocarditis.
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