CTICasesLevetiracetam (Keppra)-Induced Eosinophilic Pneumonia
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Imaging findings
Extensive ground-glass opacity throughout both lungs, with some areas of confluence and very fine nodularity. No evidence of pulmonary embolism.
Key takeaways
This case demonstrates levetiracetam (Keppra)-induced eosinophilic pneumonia, a drug-induced lung injury that can present with dyspnea, hypoxia, and eosinophilia, often after recent changes in medication or steroid taper. The imaging typically shows diffuse ground-glass opacities. Rapid clinical improvement and normalization of eosinophil count upon discontinuation of the offending drug and initiation of steroids strongly support the diagnosis, obviating the need for further imaging or invasive procedures.
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