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Unicentric Castleman's Disease (Hyaline Vascular Type)

Unicentric Castleman's Disease (Hyaline Vascular Type)▶ Watch on YouTube — age-restricted, cannot embed here

Imaging findings

CT demonstrates extensive, substantially enhancing lymph node enlargement, particularly in the right supraclavicular and para-aortic regions. PET-CT shows FDG avidity associated with the supraclavicular disease. Pathology was consistent with the hyaline vascular type.

Key takeaways

Hyaline vascular type Castleman's disease can present with substantially enhancing lymph nodes, often in a unicentric distribution. FDG avidity may be seen on PET-CT. Treatment may involve resection or rituximab, depending on the extent and type of disease.

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