CTICasesTuberous Sclerosis
Imaging findings
CT chest shows multiple thin-walled, round pulmonary cysts uniformly distributed throughout both lungs, associated with scattered small, fuzzy nodular opacities likely representing multifocal micronodular pneumocyte hyperplasia (MMPH). Renal CT shows multiple bilateral low-attenuation masses containing macroscopic fat, diagnostic of renal angiomyolipomas (AMLs).
Key takeaways
Tuberous sclerosis complex (TSC) is a multi-system neurocutaneous disorder. Thoracic manifestations include lymphangioleiomyomatosis (LAM), which presents with diffuse thin-walled lung cysts, and MMPH, presenting with small ground-glass nodules. The presence of renal angiomyolipomas is a strong diagnostic clue.
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