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Adenocarcinoma with Lymphangitic Carcinomatosis

Imaging findings

Serial CT chest scans show persistent, non-resolving consolidation in the right upper lobe, associated with nodular, smooth interlobular septal thickening and peribronchovascular cuffing extending from the hilum, representing lymphangitic carcinomatosis.

Key takeaways

Persistent consolidative opacity that fails to resolve with antibiotic therapy should raise concern for primary lung adenocarcinoma. When accompanied by nodular septal thickening, it represents lymphangitic spread, which can mimic pulmonary edema or organizing pneumonia.

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