CTICasesSilo Filler's Disease
Imaging findings
CT chest shows severe, upper-lobe-predominant bronchiectasis, mosaic attenuation representing small airway air trapping, and progressive lower-lobe subpleural reticulation, in a patient with a remote history of nitrogen oxide gas inhalation from silage.
Key takeaways
Silo filler's disease is an occupational lung injury caused by the inhalation of toxic nitrogen dioxide gas produced by fermenting silage. The acute chemical burn leads to pulmonary edema and DAD, while survivors can develop chronic bronchiolitis obliterans (small airway disease) and subsequent upper-lobe bronchiectasis and progressive fibrosis.
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