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Permeability Pulmonary Edema in Streptococcal Toxic Shock

Imaging findings

CT chest shows bilateral, diffuse interlobular septal thickening (Kerley B lines) and alveolar ground-glass opacities, without pleural effusions, cardiomegaly, or focal lobar pneumonia. The patient had Group A Streptococcus bacteremia and toxic shock.

Key takeaways

Septic shock and toxic shock syndrome (e.g., from Group A Streptococcus) can cause severe endothelial damage and increased microvascular permeability, leading to non-cardiogenic pulmonary edema (ARDS). This presents with septal lines and ground glass without signs of left heart failure.

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