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Solitary Metastasis of Renal Cell Carcinoma

Imaging findings

Chest CT shows a small, vascular-appearing soft-tissue mass in the posterior mediastinum that has grown significantly over two years. MRI demonstrates a hypervascular, heterogeneous mass with avid contrast enhancement in the posterior mediastinum. The patient has a history of prior right nephrectomy for renal cell carcinoma. Pathology of the resected mass confirms metastatic renal cell carcinoma.

Key takeaways

Renal cell carcinoma (RCC) is famous for its hypervascular metastases, which can occur many years after nephrectomy and involve unusual sites. A solitary hypervascular mass in the posterior mediastinum can easily mimic a neurogenic tumor (such as a schwannoma or paraganglioma). In any patient with a history of RCC, metastatic disease must be ruled out.

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