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Extramedullary hematopoiesis

Imaging findings

Chest CT shows demineralized, expanded, and porous ribs and vertebral bodies, associated with multiple large, symmetric, homogeneous, high-attenuation paraspinal soft tissue masses, and a dense liver from secondary hemochromatosis.

Key takeaways

Extramedullary hematopoiesis is a compensatory response to chronic anemia. It presents as lobulated, paraspinal soft tissue masses arising from marrow leakage through porous cortical bone.

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