CTICasesPembrolizumab-Induced Organizing Pneumonia
Imaging findings
Chest CT demonstrates peripheral, modular, and band-like areas of consolidation with air bronchograms, showing a predilection for the lung periphery and displaying characteristic arc-like or arching configurations.
Key takeaways
Novel cancer immunotherapies, such as immune checkpoint inhibitors like pembrolizumab, are well-known causes of drug-induced lung injury. These toxicities frequently manifest as an organizing pneumonia pattern, which is characterized by peripheral band-like consolidations and responds well to steroid therapy and drug cessation.
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