CTICasesDiffuse Alveolar Hemorrhage (DAH) post-Donor Lymphocyte Infusion
▶ Watch on YouTube — age-restricted, cannot embed here
Imaging findings
Chest radiographs show acute respiratory illness with extensive opacities, particularly in the lower lung zones, which improve over several days. A subsequent CT demonstrates residual findings. Bronchoscopy findings included bloody fluid increasing from all lobes.
Key takeaways
Diffuse alveolar hemorrhage (DAH) should be considered in immunocompromised patients, such as those with acute myeloid leukemia (AML) post-stem cell transplantation. DAH can be associated with donor lymphocyte infusion (DLI), even years after transplant, potentially as a manifestation of a graft-versus-tumor reaction. Rapid improvement after steroid treatment is typical.
AI-assisted summary — may contain errors. Verify against the source video. Learn more
More from this webinar
- Infected Breast Reduction Seroma / AbscessIatrogenic
- Breast Cancer Recurrence (Internal Mammary Lymph Node Metastasis)Neoplastic
- Cement Embolization to Pulmonary Arteries after VertebroplastyIatrogenic
- Granulomatosis with Polyangiitis (GPA) with Airway StenosisAutoimmune
- Tuberculous Tracheobronchitis and Pulmonary TuberculosisInfection
- Non-Functioning Mediastinal Paraganglioma with Pulmonary EmbolismNeoplastic
- Incidental Mediastinal ParagangliomaNeoplastic
- Mediastinal Fat InfarctionArtifact
See all cases from May 28, 2016 →