CTICasesMultifocal Synchronous Lung Adenocarcinomas
Imaging findings
CT chest shows dozens of bilateral ground-glass, subsolid, and solid pulmonary nodules containing internal bubbly lucencies (pseudo-cavitation) scattered throughout both lungs. Biopsy confirmed multifocal synchronous primary adenocarcinomas.
Key takeaways
Multifocal primary lung adenocarcinomas represent a 'field cancerization' effect, commonly seen in smokers. They present as multiple ground-glass or subsolid nodules that can contain internal bubbly lucencies. Genetic analysis typically demonstrates different clonal mutations, confirming separate primaries.
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