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Right Middle Lobe Collapse from Sarcoid Lymphadenopathy

Imaging findings

CT chest shows right middle lobe collapse, mediastinal/hilar adenopathy with amorphous calcification, and multiple perilymphatic lung nodules. Bronchoscopy shows extrinsic compression of the middle lobe bronchus origin by an enlarged node and mucosal granulomas.

Key takeaways

Although rare, sarcoidosis can cause lobar collapse (typically right middle lobe syndrome) due to extrinsic airway compression from enlarged, calcified lymph nodes. Submucosal granulomatous involvement of the airway wall can also contribute to bronchial narrowing.

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