CTICasesMiliary Myeloma in the Lungs
▶ Watch on YouTube — age-restricted, cannot embed here
Imaging findings
A woman treated for myeloma, with a history of multiple stem cell transplants, initially had clear lungs. She developed shortness of breath and fine nodular lung disease that progressed rapidly over a week, becoming increasingly confluent, with associated ground-glass smearing and pleural effusions. Initially suspected to be Candida glabrata due to its miliary pattern in an immunocompromised patient.
Key takeaways
Autopsy revealed that the miliary nodular lung disease was entirely composed of plasma cells, confirming it as the most dramatic extraosseous miliary myeloma in the lungs the presenter had ever seen. The stem cell transplant process may sensitize individuals to these extraosseous manifestations, potentially by attracting abnormal plasma cells to the pulmonary endothelium.
AI-assisted summary — may contain errors. Verify against the source video. Learn more
More from this webinar
- Fat Embolism SyndromeTrauma
- Dystrophic Calcification from Rhabdomyolysis and Pulmonary Interstitial EmphysemaMetabolic
- Nocardiosis in a Heart Transplant PatientInfection
- Pleuroparenchymal Fibroelastosis as a Manifestation of Graft-versus-Host DiseaseILD
- Synchronous Lung Cancer and Pulmonary HamartomaNeoplastic
- Variant Coronary Artery in the Ligament of MarshallCongenital
- Job's Syndrome (Hyper-IgE Syndrome) with Chronic Staphylococcal InfectionsAutoimmune
- Squamous Cell Carcinoma Obstructing Bronchus IntermediusNeoplastic
See all cases from March 4, 2016 →
Related Neoplastic cases
- Diffuse Large B-cell Lymphoma with Myocardial and Pulmonary Involvement
- Thymoma with Paraneoplastic Pure Red Cell Aplasia
- Hidden Lung Cancer
- Pulmonary Adenocarcinoma with Retained Acupuncture Needles
- Extensive Lymphoma with Extrapleural Paraspinal Involvement
- Obstructive Left Upper Lobe Collapse (Carcinoid and Adenocarcinoma)