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Miliary histoplasmosis

Imaging findings

Chest radiograph shows mild hazy lung zones, while high-resolution CT shows diffuse, innumerable tiny miliary nodules scattered throughout both lungs in a kidney transplant recipient. Bone marrow biopsy and antigen testing confirmed disseminated histoplasmosis.

Key takeaways

Miliary histoplasmosis is a severe, life-threatening manifestation of disseminated histoplasmosis in immunocompromised hosts. Because the miliary nodules are extremely small, they can be easily overlooked on chest radiographs, necessitating CT for early diagnosis.

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