CTICasesOllier Disease
Imaging findings
Chest radiograph and extremity films in a young female in her 30s demonstrate widespread, expansile, and 'bubbly' cartilaginous bone lesions (enchondromas) involving the proximal left humerus and multiple metacarpals and phalanges of the left hand. The right humerus has been completely replaced by an oncological prosthesis due to malignant transformation of a prior enchondroma into a chondrosarcoma. CT shows focal thinning and expansion of the humeral cortex.
Key takeaways
Ollier disease (multiple enchondromatosis) is a rare, non-hereditary congenital disorder characterized by multiple benign cartilaginous tumors (enchondromas) located primarily within the metaphyses and diaphyses of long bones and small bones of the hands and feet. The major clinical concern is the high risk of malignant transformation into chondrosarcoma (occurring in 25-30% of patients), which requires close monitoring and prompt surgical resection/reconstruction.
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