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Malignant Mesothelioma with Environmental Erionite Exposure and Post-Pneumonectomy Complications

Malignant Mesothelioma with Environmental Erionite Exposure and Post-Pneumonectomy Complications▶ Watch on YouTube — age-restricted, cannot embed here

Imaging findings

A young man in his 40s from a village known for erionite exposure presented with a large hydropneumothorax and a prominent fluid level. Post-extrapleural pneumonectomy, radiographs showed an unusual contour suggestive of liver herniation rather than a normal neodiaphragm. Subsequent imaging confirmed failure of the neodiaphragm with liver herniation into the thorax. After a second diaphragm installation, the patient developed a dramatic mediastinal shift due to recurrent fluid accumulation. Lymphangiography revealed extravasation of contrast into the pleural space, confirming a chylothorax.

Key takeaways

This case illustrates an unusual presentation of malignant mesothelioma in a young man, linked to environmental exposure to erionite in his village in Mexico (similar to exposures in Turkey). The patient experienced severe post-surgical complications following extrapleural pneumonectomy, including early failure of the neodiaphragm with liver herniation, requiring re-operation. Subsequently, he developed a chylothorax, managed with diet restriction and drainage. The case highlights the complex clinical course and management challenges in environmentally-linked mesothelioma.

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