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Rapid Cavitary Lung Destruction in COVID-19 ARDS

Imaging findings

Serial chest radiographs in an intubated patient with COVID-19 ARDS show rapid development of giant cystic spaces/pneumatoceles in both lungs over two weeks, representing inflammatory necrosis and ventilator-induced barotrauma.

Key takeaways

Severe viral ARDS (such as COVID-19) can cause necrotizing lung injury. When combined with mechanical ventilation, this can lead to rapid pulmonary destruction and the formation of large cystic pneumatoceles, which are high risk for pneumothorax.

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