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Solitary Renal Cell Carcinoma Metastasis to the Anterior Mediastinum

Imaging findings

CT shows an isolated, hypervascular, enhancing anterior mediastinal nodule with surrounding reactive lymphadenopathy in a patient who previously underwent nephrectomy for renal cell carcinoma. Biopsy and resection confirmed a solitary metastasis.

Key takeaways

Renal cell carcinoma is notorious for late, atypical metastatic presentations. A solitary hypervascular metastasis to the anterior mediastinum can mimic a primary thymoma or thyroid mass, requiring careful correlation with history and biopsy.

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